Steroid-Induced Sigmoid Diverticular Perforation in a Patient with Temporal Arteritis: A Rare Clinical Pathology

نویسندگان

  • Bulent Kaya
  • Orhan Aras
  • Orhan Bat
  • Nuriye Esen Bulut
  • Kemal Memisoglu
چکیده

Corticosteroids are used in the treatment of many rheumatological diseases including temporal arteritis. The gastrointestinal perforation during corticosteroid treatment is a serious complication. Colon perforation after steroid use was first reported by Beck et al in 1950.1 Although the pathophysiological mechanism is not understood clearly, it is claimed that steroids probably by disturbing the intestinal mucosal barrier, facilitate the intestinal perforation. The long term treatment with corticosteroids increases the risk of colon perforation. We are presenting a patient who was taking corticosteroid due to temporal arteritis for two years and operated with sigmoid diverticular perforation.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Free Perforation of Sigmoid Colon Secondary to Invasive Mucormycosis in a Critically Ill Patient

Mucormycosis is a clinical entity attributed to opportunistic fungal infection of order Mucorales. This includes several pathogenic subtypes. It commonly affects the rhinocerebral sites and the immunocompromized patients with devastating results. Visceral mucormycosis is a relatively rare complication. We report the first free sigmoid colon perforation secondary to invasive mucormycosis and dis...

متن کامل

Subcutaneous emphysema of the neck, chest, and abdomen as a symptom of colonic diverticular perforation into the retroperitoneum

We describe a rare case of a patient with colonic diverticular perforation manifested only by subcutaneous emphysema of the neck, chest, and abdomen, as visualized by a computed tomography (CT) scan. The 76-year-old female patient with a history of internal diseases was urgently admitted to the Clinic of Internal Diseases due to a urinary tract infection. During the hospitalization, further dia...

متن کامل

Pneumomediastinum as a presenting symptom of perforated sigmoid cancer: a case report

We report a rare case of spontaneous pneumomediastinum due to perforation of sigmoid cancer in a patient suffering from Vogt-Koyanagi-Harada syndrome and temporal arteritis, two rare diseases. This patient, who generally receives corticosteroid and methotrexate therapy, was admitted to hospital with vague abdominal and left flank pain, urinary disorders and low grade fever one day prior to admi...

متن کامل

Pathological changes in temporal arteries removed from unselected cadavers.

Progressive degenerative changes in ageing temporal arteries are described. These changes are usually severe in elderly patients, hence their presence in diagnostic biopsies provides no evidence of temporal arteritis past or present. In two patients in the series of random necropsies examined there were changes in the temporal arteries identical with those seen in patients known to have suffere...

متن کامل

Jejunal diverticula with perforation in non steroidal anti inflammatory drug user: A case report

INTRODUCTION Multiple diverticulosis of the jejunum constitutes an uncommon pathology of the small bowel. The disease is often asymptomatic and must be taken into consideration in cases of unexplained malabsorption, anemia, chronic abdominal pain and discomfort. CASE PRESENTAION We are thereby reporting a 50yr patient on chronic NSAID ingestion presenting to us with acute abdomen. On explorat...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 5  شماره 

صفحات  -

تاریخ انتشار 2012